Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22696839 | 1.00 | MAPK1 (0.66) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL22696886 | 0.98 | MAPK1 (0.66) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL21238181 | 0.98 | MAPK1 (0.66) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL28191498 | 0.95 | GABRA1 (0.70) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL28191495 | 0.95 | GABRA1 (0.70) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL28191497 | 0.90 | MAPK1 (0.62) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL28191500 | 0.90 | MAPK1 (0.62) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL16923418 | 0.88 | MAPK1 (0.57) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL16923372 | 0.88 | GABRA1 (0.64) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL22259427 | 0.87 | GABRA1 (0.63) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747869-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-12-09 | — | — | EP | disclosed |