Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329545 | 0.86 | PRMT5 (0.54) | PRMT5MAPTCDK1CDK4CCND1 | |
| SCHEMBL19329452 | 0.86 | PRMT5 (0.56) | PRMT5MAPTCDK1CDK4CCND1 | |
| SCHEMBL22968017 | 0.76 | CYP4F2 (0.44) | TRPC6CYP4F2CYP4A11 | |
| SCHEMBL19329622 | 0.74 | PRMT5 (0.48) | PRMT5LMNASMN1; SMN2ALDH1A1TLR7 | |
| SCHEMBL19346779 | 0.69 | PLAT (0.43) | PRMT5CDK4CCND1CDK2LMNA | |
| SCHEMBL22968108 | 0.69 | CYP4A11 (0.70) | CYP4F2CYP4A11 | |
| SCHEMBL17300704 | 0.68 | CNR2 (0.41) | PRMT5 | |
| SCHEMBL1911868 | 0.68 | MAPK14 (0.51) | MAPTLMNASMN1; SMN2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL19329370 | 0.68 | PLAT (0.42) | PRMT5CDK4CCND1CDK2LMNA | |
| SCHEMBL6710666 | 0.68 | CHRM4 (0.49) | MAPTLMNAALDH1A1GLATRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426351-B1 | BENZOPIPERIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND HEMOGLOBINOPATHIES | CTXT PTY LTD (AU) | 2020-12-09 | — | — | EP | disclosed |