Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15351178 | 0.83 | CHRNB2 (0.39) | — | |
| SCHEMBL22968018 | 0.78 | SSTR4 (0.48) | CYP4F2CYP4A11IRAK4F10IKBKE | |
| SCHEMBL22968108 | 0.77 | CYP4A11 (0.70) | CYP4F2CYP4A11 | |
| SCHEMBL22756234 | 0.76 | PRMT5 (0.51) | CYP4F2CYP4A11TRPC6 | |
| SCHEMBL19477443 | 0.72 | CYP4F2 (0.48) | CYP4F2CYP4A11IRAK4F10IKBKE | |
| SCHEMBL20590891 | 0.72 | CYP4F2 (0.51) | CYP4F2CYP4A11F10MEN1KMT2A | |
| SCHEMBL14771896 | 0.72 | IKBKE (0.49) | IKBKETBK1 | |
| SCHEMBL23434873 | 0.71 | IRAK4 (0.45) | CYP4F2CYP4A11IRAK4F10IKBKE | |
| SCHEMBL16094190 | 0.71 | GPR119 (0.46) | CHEK2 | |
| SCHEMBL791389 | 0.70 | CYP2C9 (0.53) | CYP4F2CYP4A11F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040062-A1 | AZOLE-SUBSTITUTED PYRIDINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040062-A1 | AZOLE-SUBSTITUTED PYRIDINE COMPOUND | CYP2F1, CYP21A2, CYP11B1 | CYP4F2 8/4885CYP4A11 13/4885TRPC6 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.