Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329311 | 0.86 | PRMT5 (0.57) | PRMT5NAMPTMAPTIKBKBGPR119 | |
| SCHEMBL19329299 | 0.73 | GPR119 (0.59) | PRMT5MAPTGPR119 | |
| SCHEMBL15830041 | 0.71 | PRMT5 (0.49) | PRMT5NAMPTIKBKBCYP4F2CYP4A11 | |
| SCHEMBL31370464 | 0.71 | NAMPT (0.57) | NAMPTIKBKBGPR119CYP4F2CYP4A11 | |
| SCHEMBL21297230 | 0.71 | PRMT5 (0.49) | PRMT5NAMPTIKBKBCYP4F2CYP4A11 | |
| SCHEMBL15114919 | 0.69 | NAMPT (0.45) | PRMT5NAMPTIKBKBGPR119CYP4F2 | |
| SCHEMBL4263974 | 0.69 | MAPT (0.38) | MAPT | |
| SCHEMBL21566655 | 0.69 | GPR119 (0.44) | PRMT5NAMPTIKBKBGPR119CYP4F2 | |
| SCHEMBL2094409 | 0.69 | HRH3 (0.49) | NAMPTIKBKBCYP4F2CYP4A11 | |
| SCHEMBL25113414 | 0.69 | HRH3 (0.50) | NAMPTIKBKBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426351-B1 | BENZOPIPERIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER AND HEMOGLOBINOPATHIES | CTXT PTY LTD (AU) | 2020-12-09 | — | — | EP | disclosed |