Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757345 | 0.91 | ADORA3 (0.49) | ADORA3ADORA1ADORA2BADORA2ATSHR | |
| SCHEMBL22757370 | 0.90 | PI4KA (0.44) | ADORA3ADORA1ADORA2BADORA2ALMNA | |
| SCHEMBL22757382 | 0.87 | ADORA3 (0.50) | ADORA3ADORA1ADORA2BADORA2ATSHR | |
| SCHEMBL24601011 | 0.82 | ADORA3 (0.57) | ADORA3ADORA1ADORA2ATSHRLMNA | |
| SCHEMBL14111376 | 0.82 | ADORA3 (0.56) | ADORA3ADORA1ADORA2BADORA2ATSHR | |
| SCHEMBL14086537 | 0.82 | ADORA3 (0.56) | ADORA3ADORA1ADORA2BADORA2ATSHR | |
| SCHEMBL22757368 | 0.82 | PI4KA (0.40) | ADORA3ADORA2BADORA2ALMNAAHCY | |
| SCHEMBL14111548 | 0.81 | ADORA3 (0.55) | ADORA3ADORA1ADORA2BADORA2ATSHR | |
| SCHEMBL14086536 | 0.81 | ADORA3 (0.55) | ADORA3ADORA1ADORA2BADORA2ATSHR | |
| SCHEMBL22750501 | 0.80 | ADORA3 (0.61) | ADORA3ADORA1ADORA2BADORA2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |