Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 17/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.58 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358011 | 0.89 | ADORA3 (0.69) | ADORA3ADORA1TMIGD3HRH2HTR5A | |
| SCHEMBL20122108 | 0.89 | ADORA3 (0.69) | ADORA3ADORA1TMIGD3HRH2HTR5A | |
| SCHEMBL22757352 | 0.87 | ADORA3 (0.54) | ADORA3ADORA1HRH2HTR5AADORA2A | |
| SCHEMBL22757376 | 0.84 | ADORA3 (0.56) | ADORA3ADORA1TMIGD3HRH2HTR5A | |
| SCHEMBL18353149 | 0.81 | ADORA3 (0.60) | ADORA3ADORA1TMIGD3HRH2HTR5A | |
| SCHEMBL21758637 | 0.80 | ADORA3 (0.65) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL20122150 | 0.80 | ADORA3 (0.65) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL29575031 | 0.79 | ADORA3 (0.46) | ADORA3ADORA1TMIGD3ADORA2A | |
| SCHEMBL20122141 | 0.79 | HRH2 (0.51) | ADORA3ADORA1TMIGD3HRH2HTR5A | |
| SCHEMBL16774130 | 0.79 | HRH2 (0.51) | ADORA3ADORA1TMIGD3HRH2HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |