Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 20/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22750598 | 1.00 | ADORA1 (0.65) | ADORA1ADORA3ADORA2BADORA2AADRA2A | |
| SCHEMBL22757400 | 0.90 | ADORA3 (0.60) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL22750526 | 0.90 | ADORA3 (0.60) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL22750672 | 0.89 | ADORA3 (0.59) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL22757390 | 0.88 | ADORA3 (0.53) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL22757449 | 0.88 | ADORA3 (0.53) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL22757447 | 0.87 | ADORA3 (0.77) | ADORA1ADORA3ADORA2BADORA2AADRA2A | |
| SCHEMBL22757374 | 0.87 | ADORA3 (0.77) | ADORA1ADORA3ADORA2BADORA2AADRA2A | |
| SCHEMBL22750605 | 0.87 | ADORA3 (0.77) | ADORA1ADORA3ADORA2BADORA2AADRA2A | |
| SCHEMBL22750571 | 0.86 | ADORA3 (0.65) | ADORA1ADORA3ADORA2BADORA2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |