Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525247 | 0.81 | ALDH1A1 (0.54) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL28880428 | 0.80 | TSHR (0.69) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL6293462 | 0.78 | MAPT (0.70) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL6290020 | 0.78 | MAPT (0.70) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL27843129 | 0.78 | KDM4E (0.69) | KDM4EMAPTALDH1A1GAANPC1 | |
| SCHEMBL6716893 | 0.78 | HPGD (0.61) | MAPTALDH1A1GAANPC1RAB9A | |
| SCHEMBL22169225 | 0.78 | HDAC1 (0.74) | — | |
| SCHEMBL27841831 | 0.78 | POLB (0.68) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL890383 | 0.78 | CYP1A2 (0.70) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL2627998 | 0.78 | KMT2A (0.59) | KDM4EMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247758-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC INFECTIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-12-10 | — | — | WO | disclosed |