Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.47 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760129 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22760130 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22760423 | 0.83 | MAPT (0.46) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22748277 | 0.81 | MEN1 (0.46) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL27346529 | 0.80 | RECQL (0.48) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22760562 | 0.78 | ALDH1A1 (0.67) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22760543 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22760541 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAMAPK8MAT2A | |
| SCHEMBL22760420 | 0.76 | MAPT (0.47) | ALDH1A1MAPTGAAMAT2ATP53 | |
| SCHEMBL22760558 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAMAPK8MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |