Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747897 | 0.92 | FOLH1 (0.40) | FOLH1MAPK8MAPK9MAPTMAPK10 | |
| SCHEMBL22760486 | 0.90 | FOLH1 (0.43) | FOLH1MAPK8MAPK9MAPTMAPK10 | |
| SCHEMBL22760195 | 0.89 | MAPT (0.49) | MAPK8MAPK9MAPTMAPK10ALDH1A1 | |
| SCHEMBL22748245 | 0.89 | FOLH1 (0.42) | FOLH1MAPK8MAPK9MAPTMAPK10 | |
| SCHEMBL22748283 | 0.89 | FOLH1 (0.42) | FOLH1MAPK8MAPK9MAPTMAPK10 | |
| SCHEMBL22747833 | 0.87 | FOLH1 (0.41) | FOLH1MAPK8MAPK9MAPTMAPK10 | |
| SCHEMBL22747841 | 0.87 | MAPK8 (0.52) | FOLH1MAPK8MAPK9MAPTALDH1A1 | |
| SCHEMBL22760555 | 0.85 | FOLH1 (0.39) | FOLH1MAPK8MAPK9MAPTMAPK10 | |
| SCHEMBL22760122 | 0.78 | MAPT (0.49) | MAPK8MAPK9MAPTMAPK10ALDH1A1 | |
| SCHEMBL22760225 | 0.78 | FOLH1 (0.44) | FOLH1MAPK8MAPK9MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |