SCHEMBL2276121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2276126	1.00	NPR3 (0.37)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL14204461	0.89	HIF1A (0.38)	HIF1AAAK1ROCK1BACE1CYP19A1
	SCHEMBL2282145	0.86	MAPK14 (0.41)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL2282138	0.86	MAPK14 (0.41)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL2282216	0.83	MAPK14 (0.40)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL2282213	0.83	MAPK14 (0.40)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL2278681	0.81	MAPK14 (0.45)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL2278687	0.81	MAPK14 (0.45)	NPR3HIF1AMAPK14MAPK13MAPK12
	SCHEMBL2276175	0.80	MAPK14 (0.45)	NPR3MAPK14MAPK13MAPK12MAPK11
	SCHEMBL2276180	0.80	MAPK14 (0.45)	NPR3MAPK14MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.