Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.30 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19193815 | 0.86 | LPAR5 (0.45) | LPAR5P2RY10LPAR1LPAR3LAP3 | |
| SCHEMBL22489044 | 0.86 | LPAR5 (0.45) | LPAR5P2RY10LPAR1LPAR3LAP3 | |
| SCHEMBL22899072 | 0.86 | LPAR5 (0.45) | LPAR5P2RY10LPAR1LPAR3LAP3 | |
| SCHEMBL22812370 | 0.84 | LPAR5 (0.43) | LPAR5P2RY10TLR2LPAR3LAP3 | |
| SCHEMBL22489070 | 0.84 | LPAR5 (0.46) | LPAR5P2RY10PLA2G2ATLR2LPAR1 | |
| SCHEMBL22899109 | 0.84 | LPAR5 (0.46) | LPAR5P2RY10PLA2G2ATLR2LPAR1 | |
| SCHEMBL23135176 | 0.84 | LPAR5 (0.39) | LPAR5 | |
| SCHEMBL18294593 | 0.84 | LPAR5 (0.47) | LPAR5P2RY10LPAR1LPAR3LAP3 | |
| SCHEMBL24696406 | 0.82 | LPAR5 (0.46) | LPAR5P2RY10LPAR1LPAR3LAP3 | |
| SCHEMBL24992326 | 0.81 | LPAR5 (0.40) | LPAR5P2RY10LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820985-B2 | Modified oligonucleotides with increased stability | UNIVERSITY OF MASSACHUSETTS (US) | 2023-11-21 | — | — | US | disclosed |
| US-20200385740-A1 | MODIFIED OLIGONUCLEOTIDES WITH INCREASED STABILITY | UNIVERSITY OF MASSACHUSETTS | 2020-12-10 | — | — | US | disclosed |