Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294593 | 0.92 | LPAR5 (0.47) | LPAR5LAP3P2RY10HSD17B10LPAR6 | |
| SCHEMBL19193914 | 0.87 | LPAR5 (0.44) | LPAR5LAP3P2RY10HSD17B10LPAR6 | |
| SCHEMBL18198276 | 0.86 | LPAR5 (0.43) | LPAR5LAP3P2RY10HSD17B10 | |
| SCHEMBL25699519 | 0.84 | LPAR5 (0.42) | LPAR5LAP3P2RY10HSD17B10 | |
| SCHEMBL21186492 | 0.83 | LPAR5 (0.41) | LPAR5LAP3P2RY10 | |
| SCHEMBL25600824 | 0.83 | LPAR5 (0.44) | LPAR5LAP3P2RY10HSD17B10LPAR6 | |
| SCHEMBL22761483 | 0.82 | LPAR5 (0.47) | LPAR5LAP3P2RY10LPAR6LPAR1 | |
| SCHEMBL24992326 | 0.82 | LPAR5 (0.40) | LPAR5LAP3P2RY10 | |
| SCHEMBL24137155 | 0.81 | LPAR5 (0.46) | LPAR5LAP3P2RY10HSD17B10LPAR6 | |
| SCHEMBL27106059 | 0.81 | LPAR5 (0.51) | LPAR5LAP3P2RY10HSD17B10LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256565-A2 | COMPOSITIONS AND METHODS FOR DELIVERING THERAPEUTIC OLIGONUCLEOTIDES TO THE CENTRAL NERVOUS SYSTEM | ATALANTA THERAPEUTICS, INC (US) | 2022-12-08 | — | — | WO | disclosed |