Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.49 |
| ▸ | LIPE | Q05469 | 8/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15229644 | 0.84 | HCRTR1 (0.44) | HCRTR1LIPESCN9A | |
| SCHEMBL4319472 | 0.83 | ALOX5AP (0.47) | ALOX5APFEN1 | |
| SCHEMBL4319486 | 0.83 | ALOX5AP (0.47) | ALOX5APFEN1 | |
| SCHEMBL4320534 | 0.83 | ALOX5AP (0.47) | ALOX5APFEN1 | |
| SCHEMBL5149728 | 0.82 | ALOX5AP (0.47) | ALOX5APFEN1 | |
| SCHEMBL10121579 | 0.82 | HCRTR1 (0.42) | HCRTR1LIPESCN9A | |
| SCHEMBL22761842 | 0.82 | HCRTR1 (0.55) | HCRTR1 | |
| SCHEMBL21606867 | 0.81 | LIPE (0.62) | ALOX5APFEN1LIPEBCHE | |
| SCHEMBL29913011 | 0.81 | LIPE (0.62) | ALOX5APFEN1LIPEBCHE | |
| SCHEMBL4310636 | 0.81 | ALOX5AP (0.47) | ALOX5APFEN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247447-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES, COMPOSITIONS AND METHODS AS OREXIN ANTAGONISTS | HAGER BIOSCIENCES, LLC (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2020247445-A1 | IMIDAZOLO DERIVATIVES, COMPOSITIONS AND METHODS AS OREXIN ANTAGONISTS | HAGER BIOSCIENCES, LLC (US) | 2020-12-10 | — | — | WO | disclosed |