SCHEMBL2276349

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2279331	0.77	ALDH1A1 (0.45)	SMN1; SMN2MAPTKDM4ELMNAALDH1A1
	SCHEMBL12373448	0.77	ALDH1A1 (0.39)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL4108323	0.74	KDM4E (0.36)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL4120589	0.74	KDM4E (0.38)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL4130076	0.73	SMN1; SMN2 (0.50)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL1706898	0.70	KDM4E (0.41)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL12806867	0.70	ALDH1A1 (0.46)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL13466282	0.69	PDE2A (0.33)	SMN1; SMN2MAPTKDM4ELMNACYP2C9
	SCHEMBL30995709	0.69	ALDH1A1 (0.57)	SMN1; SMN2HTTMAPTKDM4ELMNA
	SCHEMBL13242970	0.69	ALDH1A1 (0.45)	SMN1; SMN2HTTMAPTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.