SCHEMBL2276402

SCHEMBL2276402

O=C(c1ccccc1)C(O)Br

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.58
CES2 O00748 5/20 0.58
LMNA P02545 2/20 0.58
TSHR P16473 2/20 0.55
DAO P14920 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
TDP1 Q9NUW8 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ALKBH5 Q6P6C2 1/20 0.48
MDM2 Q00987 1/20 0.48
ALDH1A1 P00352 2/20 0.48
SRD5A2 P31213 1/20 0.46
PTPN1 P18031 1/20 0.44
GSK3B P49841 1/20 0.44
CYP3A4 P08684 3/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44
PARP1 P09874 1/20 0.44
CYP2C19 P33261 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9157738 0.82 TDP1 (0.56) CES1CES2LMNATSHRDAO
SCHEMBL379271 0.82 GSK3B (0.60) CES1CES2LMNATSHRDAO
SCHEMBL330776 0.82 TDP1 (0.56) CES1CES2LMNATSHRDAO
SCHEMBL8740775 0.82 GSK3B (0.60) CES1CES2LMNATSHRDAO
SCHEMBL3703925 0.82 TDP1 (0.56) CES1CES2LMNATSHRDAO
2-Phenylphenol SCHEMBL8158881 0.82 ALDH1A1 (0.57) CES1CES2LMNATSHRDAO
SCHEMBL157066 0.79 CES1 (0.62) CES1CES2LMNATSHRDAO
SCHEMBL1549080 0.79 CES1 (0.62) CES1CES2LMNATSHRDAO
SCHEMBL24650726 0.78 TDP1 (0.52) CES1CES2LMNATSHRDAO
SCHEMBL3992793 0.78 TDP1 (0.52) CES1CES2LMNATSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036642-A Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2026-05-15 CN claimed
CN-119930627-A Preparation method of novel aminothiazole derivative containing purine structure and application of aminothiazole derivative in aspect of promoting plant growth 贵州工业职业技术学院 2025-05-06 CN claimed
CN-117297997-B High-efficiency skin tightening polypeptide composition and product application thereof 杭州湃肽生化科技有限公司 2024-03-19 CN claimed
CN-117297997-A High-efficiency skin tightening polypeptide composition and product application thereof 杭州湃肽生化科技有限公司 2023-12-29 CN claimed
CN-115536644-A Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof 广西民族大学 2022-12-30 CN claimed
EP-1567601-B1 HIGH SOLIDS, LARGE PARTICLE, CALCINED KAOLIN SLURRIES IMERYS PIGMENTS INC (US) 2019-02-20 EP claimed
CN-106008475-B Coumarin NEDD8 activating enzyme inhibitor 南京工业大学 2019-01-22 CN claimed
CN-105541810-A Coumarin NEDD8 activating enzyme inhibitor and preparation method and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2016-05-04 CN claimed
WO-2013052803-A2 METHODS AND COMPOSITIONS COMPRISING A NITRITE-REDUCTASE PROMOTER FOR TREATMENT OF MEDICAL DISORDERS AND PRESERVATION OF BLOOD PRODUCTS RADIORX, INC. (US) 2013-04-11 WO claimed
CN-101450943-B Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH 2012-11-07 CN claimed
US-7611575-B2 A slurry of calcined kaolin, which has not been subjected to mechanical grinding, has >40% by weight a particle size of >1 mu m and >40% by weight a particle size of >2 mu m and a solids content of >58% by weight; coarseness; stabilized by thickeners; fillers; extenders; coatings; paints IMERYS PIGMENTS, INC. (US) 2009-11-03 US claimed
EP-2094292-A2 NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN Ikor, Inc. (US) 2009-09-02 EP claimed
CN-101450943-A Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH (CN) 2009-06-10 CN claimed
WO-2008051689-A2 NITRIC OXIDE-BLOCKED CROSS-LINKED TETRAMERIC HEMOGLOBIN IKOR, INC. (US) 2008-05-02 WO claimed
US-20060169174-A1 A slurry of calcined kaolin, which has not been subjected to mechanical grinding, has >40% by weight a particle size of >1 mu m and >40% by weight a particle size of >2 mu m and a solids content of >58% by weight; coarseness; stabilized by thickeners; fillers; extenders; coatings; paints IMERYS USA, INC. 2006-08-03 US claimed
EP-1567601-A1 HIGH SOLIDS, LARGE PARTICLE, CALCINED KAOLIN SLURRIES Imerys Pigments, Inc. (US) 2005-08-31 EP claimed
WO-2004050773-A1 HIGH SOLIDS, LARGE PARTICLE, CALCINED KAOLIN SLURRIES IMERYS PIGMENTS, INC. (US) 2004-06-17 WO claimed
CN-122036642-A Methyl pinonate thiazole hydrazone derivative and preparation method and application thereof 江西农业大学 2026-05-15 CN disclosed
EP-0031795-A1 Hydroxyphenyl ketones CIBA-GEIGY AG (CH) 1981-07-08 EP disclosed
US-4060384-A Manufacture of leather SETON COMPANY (US) 1977-11-29 US disclosed