SCHEMBL2276423

SCHEMBL2276423

CCCCC([SiH3])(CCl)CCCC

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.35
FDPS P14324 1/20 0.34
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886534 0.82 TSHR (0.40) TSHRTDP1ALDH1A1FDPSLMNA
SCHEMBL7752834 0.77 TSHR (0.41) TSHRFDPSLMNATHRB
SCHEMBL7265091 0.77 TSHR (0.35) TSHRFDPSLMNATHRB
SCHEMBL10942777 0.76
SCHEMBL16209482 0.74 TSHR (0.47) TSHRFDPSTHRB
SCHEMBL6890492 0.71
SCHEMBL8687202 0.71 TSHR (0.50) TSHRFDPSTHRB
SCHEMBL10416462 0.71 TSHR (0.50) TSHRFDPSTHRB
SCHEMBL17351709 0.71 TSHR (0.50) TSHRFDPSTHRB
SCHEMBL10797646 0.71 TSHR (0.50) TSHRFDPSTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
EP-0068813-B1 FUNGICIDAL 1,2,4-TRIAZOLE AND IMIDAZOLE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-09-25 EP disclosed
US-4510136-A A 1-SILYLMETHYL DERIVATIVE; AGRICULTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-09 US disclosed
US-4496551-A Fungicidal imidazole derivatives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-01-29 US disclosed
EP-0068813-A2 Fungicidal 1,2,4-triazole and imidazole derivatives E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-05 EP disclosed