SCHEMBL7752834

SCHEMBL7752834

CCCCCC([SiH3])(CCCC)CCCC

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
THRB P10828 1/20 0.41
FDPS P14324 11/20 0.37
GGPS1 O95749 7/20 0.37
LMNA P02545 1/20 0.35
SMPD1 P17405 2/20 0.34
CES2 O00748 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16209482 0.97 TSHR (0.47) TSHRTHRBFDPSGGPS1SMPD1
SCHEMBL10797646 0.94 TSHR (0.50) TSHRTHRBFDPSGGPS1SMPD1
SCHEMBL10416462 0.94 TSHR (0.50) TSHRTHRBFDPSGGPS1SMPD1
SCHEMBL17351709 0.94 TSHR (0.50) TSHRTHRBFDPSGGPS1SMPD1
SCHEMBL8687202 0.94 TSHR (0.50) TSHRTHRBFDPSGGPS1SMPD1
SCHEMBL3886534 0.94 TSHR (0.40) TSHRTHRBFDPSLMNA
SCHEMBL7265091 0.88 TSHR (0.35) TSHRTHRBFDPSLMNA
SCHEMBL2276423 0.77 TSHR (0.38) TSHRTHRBFDPSLMNA
Hydrochloric Acid SCHEMBL31544530 0.77 DNM1 (0.54) TSHRTHRBFDPSGGPS1
SCHEMBL2723204 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
WO-2001060932-A1 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-08-23 WO claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US disclosed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP disclosed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN disclosed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO disclosed
WO-2001060932-A1 ANTIFOULING PAINT COMPOSITION J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-08-23 WO disclosed