Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279648 | 0.90 | P2RX3 (0.60) | P2RX3P2RX2 | |
| SCHEMBL2276461 | 0.89 | P2RX3 (0.51) | P2RX3P2RX2 | |
| SCHEMBL2276438 | 0.84 | P2RX3 (0.65) | P2RX3P2RX2 | |
| SCHEMBL2274823 | 0.81 | P2RX3 (0.56) | P2RX3P2RX2 | |
| SCHEMBL2277336 | 0.81 | P2RX3 (0.56) | P2RX3P2RX2 | |
| SCHEMBL2276299 | 0.80 | P2RX3 (0.57) | P2RX3P2RX2 | |
| SCHEMBL2279542 | 0.80 | P2RX3 (0.56) | P2RX3P2RX2 | |
| SCHEMBL2275969 | 0.79 | P2RX3 (0.58) | P2RX3P2RX2 | |
| SCHEMBL2271127 | 0.79 | P2RX3 (0.56) | P2RX3P2RX2 | |
| SCHEMBL2274925 | 0.77 | P2RX3 (0.65) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989637-B2 | Triazole-substituted arylamides as P2X3 and P2X2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2011-08-02 | — | — | US | claimed |