SCHEMBL22765713

SCHEMBL22765713

CC1CN(C2COC2)CCN1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.33
KDM2B Q8NHM5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20929305 1.00 KAT2B (0.33) KAT2BKDM2B
SCHEMBL20929306 1.00 KAT2B (0.33) KAT2BKDM2B
SCHEMBL15295255 0.78 ALDH1A1 (0.31)
SCHEMBL15295207 0.78 ALDH1A1 (0.31)
SCHEMBL21120632 0.77 ALDH1A1 (0.37) KDM2B
SCHEMBL16822613 0.75 HTR2A (0.32)
SCHEMBL10274614 0.75 ALDH1A1 (0.47)
SCHEMBL27811142 0.75 ALDH1A1 (0.42)
SCHEMBL16822468 0.75 HTR2A (0.32)
SCHEMBL28133521 0.75 DPP4 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223754-A1 COMPOUND AS AKT KINASE INHIBITOR CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2023-08-09 EP disclosed
WO-2021047584-A1 SUBSTITUTED (2-AZABICYCLO [3.1.0] HEXAN-2-YL) PYRAZOLO [1, 5-a] PYRIMIDINE AND IMIDAZO [1, 2-b] PYRIDAZINE COMPOUNDS AS TRK KINASES INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2021-03-18 WO disclosed
WO-2020247298-A2 1-PYRAZOLYL, 5-, 6- DISUBSTITUTED INDAZOLE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF MERCK SHARP & DOHME CORP. (US) 2020-12-10 WO disclosed