Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978040 | 0.80 | PSMD14 (0.43) | PSMD14GRM4KDRFLT3GSK3B | |
| SCHEMBL369216 | 0.75 | PSMD14 (0.48) | PSMD14GRM4L3MBTL1KDRFLT3 | |
| Potassium SCHEMBL3219697 | 0.73 | PSMD14 (0.47) | PSMD14GRM4L3MBTL1KDRFLT3 | |
| SCHEMBL3219684 | 0.73 | PSMD14 (0.47) | PSMD14GRM4L3MBTL1KDRFLT3 | |
| SCHEMBL7743849 | 0.71 | MAPK1 (0.50) | KDRFLT3GSK3BPRKD3PRKD2 | |
| SCHEMBL13978041 | 0.71 | PSMD14 (0.48) | PSMD14GRM4L3MBTL1KDRFLT3 | |
| SCHEMBL569155 | 0.71 | AXL (0.50) | PSMD14GRM4KDRFLT3GSK3B | |
| SCHEMBL22510135 | 0.71 | PSMD14 (0.48) | PSMD14GRM4L3MBTL1KDM4EHSP90AA1 | |
| SCHEMBL3175822 | 0.71 | PSMD14 (0.48) | PSMD14GRM4KDRFLT3GSK3B | |
| SCHEMBL19100792 | 0.71 | GRM4 (0.54) | PSMD14GRM4L3MBTL1KDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200385382-A1 | 6-AZAINDOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385382-A1 | 6-AZAINDOLE COMPOUNDS | TLR7, TLR9, TLR5 | PSMD14 4789/4885GRM4 414/4885L3MBTL1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.