Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567279 | 0.80 | HPGD (0.43) | GLP1RHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL16976283 | 0.78 | HPGD (0.40) | GLP1RHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL13743018 | 0.78 | GLP1R (0.41) | GLP1RLPAR3HPGDMEN1ALDH1A1 | |
| SCHEMBL21846024 | 0.77 | GLP1R (0.37) | GLP1RLPAR3LPAR1HPGDMEN1 | |
| SCHEMBL16328781 | 0.76 | LPAR3 (0.47) | GLP1RLPAR3LPAR1HPGDMEN1 | |
| SCHEMBL25132733 | 0.76 | BCHE (0.42) | GLP1RMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL19465313 | 0.76 | HPGD (0.46) | GLP1RHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL13566483 | 0.76 | HPGD (0.46) | GLP1RHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL22769000 | 0.76 | GLP1R (0.34) | GLP1RHPGDHTTSMN1; SMN2 | |
| SCHEMBL28103026 | 0.76 | SIRT6 (0.42) | GLP1RLPAR3LPAR1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247297-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2020-12-10 | — | — | WO | disclosed |