Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051286 | 1.00 | THRB (0.36) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL26765776 | 1.00 | THRB (0.36) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL15870835 | 1.00 | THRB (0.36) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL18823800 | 0.78 | THRB (0.38) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL10216215 | 0.78 | THRB (0.38) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL24328537 | 0.78 | THRB (0.38) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL15059696 | 0.78 | — | — | |
| SCHEMBL19841410 | 0.78 | THRB (0.38) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL13121344 | 0.78 | THRB (0.38) | THRBLMNACHRM5CHRM1CHRM3 | |
| SCHEMBL18126800 | 0.78 | THRB (0.38) | THRBLMNACHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247297-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2020-12-10 | — | — | WO | disclosed |