Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22768971 | 0.92 | TDP1 (0.64) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL17244679 | 0.91 | TDP1 (0.63) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL18133288 | 0.86 | TDP1 (0.69) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL13041591 | 0.85 | F2 (0.60) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL15258705 | 0.85 | F2 (0.60) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL24313157 | 0.84 | F2 (0.60) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL22769242 | 0.84 | TDP1 (0.54) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL10689008 | 0.84 | TDP1 (0.58) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL21524563 | 0.83 | TDP1 (0.65) | TDP1FOLH1F2PRSS1PRSS2 | |
| SCHEMBL21524559 | 0.83 | TDP1 (0.65) | TDP1FOLH1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981772-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020246602-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | 大塚製薬株式会社 | 2020-12-10 | — | — | WO | disclosed |