Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769243 | 0.91 | FOLH1 (0.45) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL22768973 | 0.87 | FOLH1 (0.52) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL24312560 | 0.87 | FOLH1 (0.52) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL24312523 | 0.87 | FOLH1 (0.52) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL24312559 | 0.82 | FOLH1 (0.60) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL24312562 | 0.82 | FOLH1 (0.54) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL22769245 | 0.80 | FOLH1 (0.47) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL24312519 | 0.79 | FOLH1 (0.48) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL24312526 | 0.79 | FOLH1 (0.49) | FOLH1CNR1PRSS1PRSS2PRSS3 | |
| SCHEMBL22768916 | 0.79 | FOLH1 (0.49) | FOLH1CNR1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020246602-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | 大塚製薬株式会社 | 2020-12-10 | — | — | WO | disclosed |