Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.60 |
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312562 | 0.94 | FOLH1 (0.54) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL22768973 | 0.91 | FOLH1 (0.52) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL24312560 | 0.91 | FOLH1 (0.52) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL24312523 | 0.91 | FOLH1 (0.52) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL22769248 | 0.88 | FOLH1 (0.65) | FOLH1TDP1CAPN1PRSS1PRSS2 | |
| SCHEMBL17244682 | 0.88 | FOLH1 (0.65) | FOLH1TDP1CAPN1PRSS1PRSS2 | |
| SCHEMBL22769223 | 0.88 | FOLH1 (0.51) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL16458328 | 0.86 | FOLH1 (0.62) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL22769221 | 0.86 | FOLH1 (0.49) | FOLH1CNR1TDP1CAPN1PRSS1 | |
| SCHEMBL24312519 | 0.85 | FOLH1 (0.48) | FOLH1CNR1TDP1CAPN1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981772-A1 | TETRA-FUNCTIONAL CHEMICAL PROBE AND METHOD FOR IDENTIFYING TARGET MEMBRANE PROTEIN FROM LIVING CELL OR LIVING TISSUE BY USING SAID PROBE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-04-13 | — | — | EP | disclosed |