Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399365 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL15434633 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL15429687 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL36997213 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL18464579 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL24768202 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL36392634 | 1.00 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL22259843 | 0.86 | NPC1 (0.38) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL20833308 | 0.86 | NPC1 (0.38) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 | |
| SCHEMBL22260399 | 0.77 | SCN10A (0.39) | SLC6A3SLC6A2SLC6A4HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872485-B1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES LTD (SG) | 2020-12-16 | — | — | EP | disclosed |