Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PPARA | Q07869 | 12/20 | 0.43 |
| ▸ | PPARG | P37231 | 11/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355029 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2PPARAPPARGTDP1 | |
| SCHEMBL11359371 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL6504667 | 0.80 | TDP1 (0.58) | SMN1; SMN2PPARAPPARGTDP1CA12 | |
| SCHEMBL4820214 | 0.78 | SMN1; SMN2 (0.69) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL8935664 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL8615615 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL2280554 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL14121845 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2PPARAPPARGTDP1MEN1 | |
| SCHEMBL3942614 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL14157506 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2PPARAPPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998462-B2 | Linkers for anchoring targeting ligands | KEREOS, INC. (US) | 2011-08-16 | — | — | US | disclosed |
| EP-2094311-A2 | IMPROVED LINKERS FOR ANCHORING TARGETING LIGANDS | KEREOS, INC. (US) | 2009-09-02 | — | — | EP | disclosed |
| US-20080305037-A1 | LINKERS FOR ANCHORING TARGETING LIGANDS | KEREOS, INC. | 2008-12-11 | — | — | US | disclosed |
| WO-2008070291-A2 | IMPROVED LINKERS FOR ANCHORING TARGETING LIGANDS | KEREOS, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305037-A1 | LINKERS FOR ANCHORING TARGETING LIGANDS | LDLR, HDLBP, FABP1 | SMN1; SMN2 4043/4885PPARA 970/4885PPARG 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.