Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 14/20 | 0.50 |
| ▸ | PPARG | P37231 | 13/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615615 | 1.00 | SMN1; SMN2 (1.00) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL4814937 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL16571461 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL14121845 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL11359371 | 0.84 | SMN1; SMN2 (0.73) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL17512446 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2TDP1MEN1KMT2APPARA | |
| SCHEMBL8935844 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL8935859 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL1171344 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2PPARAPPARG | |
| SCHEMBL11355029 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2TDP1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |