Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | TEK | Q02763 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | RHOC | P08134 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17936093 | 0.91 | MAPT (0.74) | P2RX1MAPTLCKTEKLMNA | |
| SCHEMBL22772362 | 0.86 | RHOC (0.60) | P2RX1MAPTLMNAABL1BCR | |
| SCHEMBL17818404 | 0.85 | MAPT (0.70) | P2RX1MAPTLCKTEKLMNA | |
| SCHEMBL12412184 | 0.83 | GRM5 (0.58) | P2RX1MAPTLCKTEK | |
| SCHEMBL5227631 | 0.83 | P2RX1 (1.00) | P2RX1MAPTLMNARHOCRHOA | |
| SCHEMBL17818365 | 0.82 | MAPT (0.66) | P2RX1MAPTLMNARXFP1KCNK3 | |
| SCHEMBL12412171 | 0.81 | GRM5 (0.60) | P2RX1LCKTEKLMNATRPA1 | |
| SCHEMBL3838614 | 0.81 | HDAC1 (0.66) | P2RX1MAPTRXFP1KCNK3 | |
| SCHEMBL13692719 | 0.81 | HDAC8 (0.52) | LMNAKCNK3PTGS1 | |
| SCHEMBL22772369 | 0.81 | NR2E1 (0.75) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407745-B2 | Indazole derivatives and pharmaceutical composition for preventing, alleviating or treating cancer containing the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-08-09 | — | — | US | disclosed |
| US-20200392127-A1 | NOVEL INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING CANCER CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-12-17 | — | — | US | disclosed |
| US-20200392127-A1 | NOVEL INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING CANCER CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392127-A1 | NOVEL INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING CANCER CONTAINING THE SAME | ABL1, DDR1, ABL2 | P2RX1 3220/4885MAPT 3839/4885LCK 34/4885 |
| US-11407745-B2 | Indazole derivatives and pharmaceutical composition for preventing, alleviating or treating cancer containing the same | ABL1, DDR1, ABL2 | P2RX1 3084/4885MAPT 3859/4885LCK 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.