Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4213234 | 0.91 | PRKCA (0.57) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL2277175 | 0.90 | PRKCA (0.49) | PRKCAMMP12NR1I2 | |
| SCHEMBL393188 | 0.88 | PRKCA (0.52) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL2275227 | 0.87 | PRKCA (0.47) | PRKCAMMP12NR1I2 | |
| SCHEMBL2279364 | 0.85 | PRKCA (0.44) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL2277252 | 0.85 | PRKCA (0.49) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL2277953 | 0.83 | PRKCA (0.51) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL2281723 | 0.80 | PRKCA (0.59) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL3685264 | 0.80 | PRKCA (0.59) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL4211037 | 0.80 | PRKCA (0.58) | PRKCAMMP12SCN9ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989438-B2 | Therapeutic compounds | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-08-02 | — | — | US | disclosed |