SCHEMBL2277338

SCHEMBL2277338

Cc1cccc(C)c1-c1c(C)cccc1C.Cc1ccccc1-c1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.50
TSHR P16473 1/20 0.50
ACHE P22303 1/20 0.50
NPC1 O15118 1/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
CA9 Q16790 3/20 0.45
CA7 P43166 2/20 0.45
HTR7 P34969 3/20 0.44
PDK2 Q15119 1/20 0.44
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA12 O43570 1/20 0.43
CYP2A6 P11509 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3355661 0.89 MYC (0.47) MYCTSHRACHENPC1CASP3
SCHEMBL1133067 0.88 MYC (0.56) MYCTSHRACHENPC1CASP3
SCHEMBL30354037 0.87 ACHE (0.64) TSHRACHENPC1CASP3RAB9A
SCHEMBL30169568 0.87 ACHE (0.64) TSHRACHENPC1CASP3RAB9A
SCHEMBL598761 0.87 TSHR (0.53) MYCTSHRACHENPC1CASP3
SCHEMBL197690 0.87 ACHE (0.64) TSHRACHENPC1CASP3RAB9A
SCHEMBL28899579 0.85 MYC (0.58) MYCTSHRACHENPC1CASP3
SCHEMBL6564122 0.84 ACHE (0.60) TSHRACHENPC1CASP3RAB9A
Lithium SCHEMBL31260773 0.84 ACHE (0.60) TSHRACHENPC1CASP3RAB9A
Ammonia Solution, Strong SCHEMBL842431 0.84 ACHE (0.60) TSHRACHENPC1CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210322933-A1 ZWITTERION-FUNCTIONALIZED COPOLYMER HOLLOW-FIBER MEMBRANES AND ASSOCIATED METHOD CYTIVA SWEDEN AB (SE) 2021-10-21 US disclosed
EP-3794056-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES Cytiva Sweden AB (SE) 2021-03-24 EP disclosed
US-20210079220-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES CYTIVA SWEDEN AB (SE) 2021-03-18 US disclosed
US-10851241-B2 Zwitterion-functionalized multicomponent copolymers and associated polymer blends and membranes CYTIVA SWEDEN AB (SE) 2020-12-01 US disclosed
EP-3142778-B1 ZWITTERION-FUNCTIONALIZED BLOCK COPOLYMER MEMBRANES AND ASSOCIATED BLOCK COPOLYMER COMPOSITION GEN ELECTRIC (US) 2019-01-30 EP disclosed
EP-3383523-A1 ZWITTERIONIC SULFONE POLYMER FLAT SHEET MEMBRANE General Electric Company (US) 2018-10-10 EP disclosed
EP-3383524-A1 ZWITTERIONIC SULFONE POLYMER BLEND AND HOLLOW-FIBER MEMBRANE General Electric Company (US) 2018-10-10 EP disclosed
US-20180258285-A1 ZWITTERION-FUNCTIONALIZED MULTICOMPONENT COPOLYMERS AND ASSOCIATED POLYMER BLENDS AND MEMBRANES GE HEALTHCARE BIO-SCIENCE AB (SE) 2018-09-13 US disclosed
EP-3221036-A1 ZWITTERION-FUNCTIONALIZED COPOLYMER HOLLOW-FIBER MEMBRANES AND ASSOCIATED METHOD General Electric Company (US) 2017-09-27 EP disclosed
WO-2017096140-A1 ZWITTERIONIC SULFONE POLYMER BLEND AND HOLLOW-FIBER MEMBRANE GENERAL ELECTRIC COMPANY (US) 2017-06-08 WO disclosed
US-20080312349-A1 METHOD OF MAKING AND USING MEMBRANE GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
US-20080203012-A1 MEMBRANE, APPARATUS, AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
US-20080207822-A1 COMPOSITION AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed
WO-2008103599-A2 COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-28 WO disclosed
US-20080142418-A1 FUNCTIONAL POLYARYLETHERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 US disclosed
US-20080142429-A1 FUNCTIONAL POLYARYLETHERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 US disclosed
US-20080142443-A1 POLYARYLETHER MEMBRANES GENERAL ELECTRIC (US) 2008-06-19 US disclosed
US-20080142442-A1 hollow fiber modules comprising blends of polyphenylene ethers block polymers and polyvinylpyrrolidone, used for blood dialysis and filtration GENERAL ELECTRIC (US) 2008-06-19 US disclosed
WO-2008073536-A1 FUNCTIONAL POLYARYLETHERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 WO disclosed
WO-2008073537-A1 FUNCTIONAL POLYARYLETERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080142429-A1 FUNCTIONAL POLYARYLETHERS CBR3, NR2E3, HRH4 MYC 1940/4885TSHR 181/4885ACHE 4550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.