SCHEMBL22773552

SCHEMBL22773552

Fc1cc(-c2c[nH]nn2)cc(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30544790 0.87
SCHEMBL30601035 0.86 KDM1A (0.43)
SCHEMBL30601033 0.84
SCHEMBL30601039 0.84
SCHEMBL30544798 0.84
SCHEMBL2024760 0.82
SCHEMBL29889806 0.81 NOTUM (0.35)
SCHEMBL29985610 0.80 NOTUM (0.42)
SCHEMBL30601032 0.80
SCHEMBL29899235 0.76 KIF11 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12291547-B2 Synthesis of 3-azido-3-deoxy-D-galactopyranose UNIVERSITé LAVAL (CA) 2025-05-06 US claimed
EP-4225752-A1 SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES Idorsia Pharmaceuticals Ltd (CH) 2023-08-16 EP claimed
CN-116348463-A Spiro derivatives of alpha-D-galactopyranoside 爱杜西亚药品有限公司 2023-06-27 CN claimed
US-20220251129-A1 SYNTHESIS OF 3-AZIDO-3-DEOXY-D-GALACTOPYRANOSE UNIVERSITé LAVAL (CA) 2022-08-11 US claimed
EP-4021904-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2022-07-06 EP claimed
EP-3983423-A1 SYNTHESIS OF 3-AZIDO-3-DEOXY-D-GALACTOPYRANOSE Université Laval (CA) 2022-04-20 EP claimed
WO-2022073969-A1 SPIRO DERIVATIVES OF ALPHA-D-GALACTOPYRANOSIDES IDORSIA PHARMACEUTICALS LTD (CH) 2022-04-14 WO claimed
WO-2020248068-A1 SYNTHESIS OF 3-AZIDO-3-DEOXY-D-GALACTOPYRANOSE UNIVERSITé LAVAL (CA) 2020-12-17 WO claimed
US-12410208-B2 (2-acetamidyl)thio-beta-D-galactopyranoside derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2025-09-09 US disclosed
US-12404295-B2 (Hetero)aryl-methyl-thio-beta-D-galactopyranoside derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2025-09-02 US disclosed
US-20250257056-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2025-08-14 US disclosed
US-12319672-B2 Alpha-D-galactopyranoside derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2025-06-03 US disclosed
US-12312362-B2 Spiro derivatives of Alpha-D-galactopyranosides IDORSIA PHARMACEUTICALS LTD (CH) 2025-05-27 US disclosed
US-12304902-B2 Hydroxyheterocycloalkane-carbamoyl derivatives IDORSIA PHARMACEUTICALS LTD (CH) 2025-05-20 US disclosed
US-20220315619-A1 (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2022-10-06 US disclosed
US-20220306674-A1 (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2022-09-29 US disclosed
US-20220281855-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2022-09-08 US disclosed
EP-4021904-A1 ALPHA-D-GALACTOPYRANOSIDE DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2022-07-06 EP disclosed
CN-114206893-A (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN disclosed
CN-114206892-A (2-acetamido) thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN disclosed