Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29550534 | 1.00 | GRIN1 (0.57) | GRIN1GRIN2B | |
| SCHEMBL28685442 | 0.82 | GRIN2B (0.53) | GRIN1GRIN2B | |
| SCHEMBL28687512 | 0.81 | GRIN2B (0.55) | GRIN1GRIN2B | |
| SCHEMBL28699350 | 0.79 | GRIN2B (0.53) | GRIN1GRIN2B | |
| SCHEMBL22775592 | 0.76 | GRIN1 (0.71) | GRIN1GRIN2B | |
| SCHEMBL29525768 | 0.76 | GRIN1 (0.71) | GRIN1GRIN2B | |
| SCHEMBL28736478 | 0.76 | GRIN1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL22775385 | 0.75 | GRIN2B (0.71) | GRIN1GRIN2B | |
| SCHEMBL22771302 | 0.75 | GRIN2B (0.64) | GRIN1GRIN2B | |
| SCHEMBL29603411 | 0.75 | GRIN2B (0.64) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983075-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020249792-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |