Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 18/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21611130 | 0.83 | GRIN2B (0.61) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL22775651 | 0.79 | GRIN1 (0.57) | GRIN2BGRIN1 | |
| SCHEMBL29550534 | 0.79 | GRIN1 (0.57) | GRIN2BGRIN1 | |
| SCHEMBL27224375 | 0.79 | GRIN2B (0.60) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL28687512 | 0.78 | GRIN2B (0.55) | GRIN2BGRIN1 | |
| SCHEMBL28685442 | 0.77 | GRIN2B (0.53) | GRIN2BGRIN1 | |
| SCHEMBL28736242 | 0.77 | GRIN1 (0.65) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL23067637 | 0.76 | GRIN2B (0.63) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL29550312 | 0.76 | GRIN2B (0.72) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL22775812 | 0.76 | GRIN2B (0.72) | GRIN2BGRIN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993868-A | Substituted pyrazolopyridinamides and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-113993868-A | Substituted pyrazolopyridinamides and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-01-28 | — | — | CN | disclosed |