Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16830487 | 0.90 | RORC (1.00) | RORC | |
| SCHEMBL16830552 | 0.85 | RORC (1.00) | RORC | |
| SCHEMBL16830485 | 0.81 | RORC (1.00) | RORC | |
| SCHEMBL16830547 | 0.81 | RORC (1.00) | RORC | |
| SCHEMBL22784485 | 0.78 | RORC (0.51) | RORC | |
| SCHEMBL16830644 | 0.78 | RORC (1.00) | RORC | |
| SCHEMBL16830683 | 0.77 | RORC (1.00) | RORC | |
| SCHEMBL16830512 | 0.77 | RORC (1.00) | RORC | |
| SCHEMBL16830503 | 0.76 | RORC (1.00) | RORC | |
| SCHEMBL16830510 | 0.76 | RORC (1.00) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113950477-B | Granulin precursor modulators and methods of use thereof | 阿库达医疗公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-3983401-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | Arkuda Therapeutics (US) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020252222-A1 | PROGRANULIN MODULATORS AND METHODS OF USING THE SAME | ARKUDA THERAPEUTICS (US) | 2020-12-17 | — | — | WO | disclosed |