Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2273779 | 1.00 | CYP1A2 (0.41) | CYP1A2TLR4AKT1SMN1; SMN2PPARG | |
| SCHEMBL2273773 | 1.00 | CYP1A2 (0.41) | CYP1A2TLR4AKT1SMN1; SMN2PPARG | |
| SCHEMBL2277755 | 1.00 | CYP1A2 (0.41) | CYP1A2TLR4AKT1SMN1; SMN2PPARG | |
| SCHEMBL2273782 | 1.00 | CYP1A2 (0.41) | CYP1A2TLR4AKT1SMN1; SMN2PPARG | |
| SCHEMBL2270788 | 0.91 | CYP1A2 (0.47) | CYP1A2TLR4AKT1PPARGLMNA | |
| SCHEMBL2270785 | 0.91 | CYP1A2 (0.47) | CYP1A2TLR4AKT1PPARGLMNA | |
| SCHEMBL2270903 | 0.90 | CYP1A2 (0.54) | CYP1A2PPARGCYP2C9MAPTKMT2A | |
| SCHEMBL2277253 | 0.90 | CYP1A2 (0.54) | CYP1A2PPARGCYP2C9MAPTKMT2A | |
| SCHEMBL15086803 | 0.90 | CYP1A2 (0.54) | CYP1A2PPARGCYP2C9MAPTKMT2A | |
| SCHEMBL2273086 | 0.90 | CYP1A2 (0.54) | CYP1A2PPARGCYP2C9MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020407-B1 | 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | JNC CORP (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-7999123-B2 | 2-oxetanone derivative and process for production thereof | JNC CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090275756-A1 | 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | CHISSO CORPORATION (JP) | 2009-11-05 | — | — | US | disclosed |
| EP-2020407-A1 | 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | Chisso Corporation (JP) | 2009-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275756-A1 | 2-OXETANONE DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | OGDH, OXGR1, OXER1 | CYP1A2 40/4885TLR4 2044/4885AKT1 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.