Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938442 | 0.87 | FUCA1 (0.36) | FUCA1 | |
| SCHEMBL18357177 | 0.81 | FUCA1 (0.58) | FUCA1 | |
| SCHEMBL18357192 | 0.81 | FUCA1 (0.58) | FUCA1 | |
| SCHEMBL16522602 | 0.81 | FUCA1 (0.58) | FUCA1 | |
| SCHEMBL16522595 | 0.81 | FUCA1 (0.58) | FUCA1 | |
| SCHEMBL23463642 | 0.80 | FUCA1 (0.30) | FUCA1 | |
| SCHEMBL14805845 | 0.80 | FUCA1 (0.34) | FUCA1 | |
| SCHEMBL24429386 | 0.80 | FUCA1 (0.30) | FUCA1 | |
| SCHEMBL24359572 | 0.80 | — | — | |
| SCHEMBL6867646 | 0.73 | FUCA1 (0.50) | FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865216-B2 | Tricyclic Gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2020-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865216-B2 | Tricyclic Gyrase inhibitors | TOP1, TOP2A, TOP2B | FUCA1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.