Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248273 | 0.89 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL28194240 | 0.87 | RIPK1 (0.81) | RIPK1 | |
| Trifluoroacetic Acid SCHEMBL20138343 | 0.87 | RIPK1 (0.96) | RIPK1 | |
| SCHEMBL25196155 | 0.85 | RIPK1 (0.81) | RIPK1 | |
| SCHEMBL18248342 | 0.85 | RIPK1 (0.88) | RIPK1 | |
| SCHEMBL18248239 | 0.82 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL18255204 | 0.82 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL18248297 | 0.82 | RIPK1 (0.93) | RIPK1 | |
| SCHEMBL18248349 | 0.82 | RIPK1 (0.98) | RIPK1 | |
| SCHEMBL20138358 | 0.82 | RIPK1 (0.89) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3298002-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-12-16 | — | — | EP | disclosed |