SCHEMBL2278045

SCHEMBL2278045

CCOC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
KDM4E B2RXH2 2/20 0.52
HPGD P15428 3/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 2/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
KMT2A Q03164 2/20 0.47
LMNA P02545 2/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GLA P06280 1/20 0.46
POLB P06746 1/20 0.46
THRB P10828 1/20 0.46
ATM Q13315 1/20 0.46
KCNN4 O15554 1/20 0.46
ALDH1A1 P00352 4/20 0.45
RECQL P46063 1/20 0.45
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10444412 0.86 GAA (0.53) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL2969420 0.84 GAA (0.51) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL28397741 0.83 KDM4E (0.50) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL9034322 0.83 KDM4E (0.50) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL14273153 0.83 GAA (0.58) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL1507628 0.81 GAA (0.53) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL5500086 0.81 KMT2A (0.55) NPC1RAB9AKMT2ALMNAMAPK1
SCHEMBL9828908 0.80 KDM4E (0.51) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL9828915 0.80 KDM4E (0.51) GAAKDM4EHPGDNPC1RAB9A
SCHEMBL28325012 0.77 KDM4E (0.48) GAAKDM4EHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1958992-B1 Phase change inks containing colorant compounds XEROX CORP (US) 2013-03-13 EP disclosed
EP-1956052-B1 Colorant compounds XEROX CORP (US) 2012-12-05 EP disclosed
US-8303671-B2 Mixture of basic dye and acid dye with wax XEROX CORPORATION (US) 2012-11-06 US disclosed
US-7997712-B2 Phase change inks containing colorant compounds XEROX CORPORATION (US) 2011-08-16 US disclosed
EP-1958992-A1 Phase change inks containing colorant compounds Xerox Corporation (US) 2008-08-20 EP disclosed
EP-1956052-A2 Colorant compounds Xerox Corporation (US) 2008-08-13 EP disclosed
US-20080186371-A1 Phase change inks containing colorant compounds XEROX CORPORATION 2008-08-07 US disclosed
US-20080184911-A1 Colorant compounds XEROX CORPORATION 2008-08-07 US disclosed