Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828915 | 1.00 | KDM4E (0.51) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL9830815 | 0.88 | LMNA (0.45) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL9830821 | 0.88 | LMNA (0.45) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL193093 | 0.87 | KCNN4 (0.44) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL5711399 | 0.87 | MEN1 (0.51) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31329451 | 0.85 | CXCR2 (0.39) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL10440896 | 0.85 | POLB (0.48) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL4034639 | 0.84 | ALDH1A1 (0.48) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL6070284 | 0.83 | KDM4E (0.45) | KDM4EGAAHPGDALDH1A1KMT2A | |
| SCHEMBL27158981 | 0.83 | CA12 (0.43) | GAAKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |