Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371526 | 0.88 | FOLH1 (0.70) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL999055 | 0.85 | FOLH1 (0.61) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL1817886 | 0.84 | FOLH1 (0.66) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL16559877 | 0.84 | FOLH1 (0.66) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL30395109 | 0.84 | FOLH1 (0.66) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL10655399 | 0.84 | FOLH1 (0.66) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL30578357 | 0.84 | FOLH1 (0.66) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| Hydrochloric Acid SCHEMBL2636111 | 0.83 | FOLH1 (0.59) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A | |
| SCHEMBL334419 | 0.82 | CYP4F2 (0.64) | FOLH1CYP2D6CYP2C9HIF1AANPEP | |
| Hydrochloric Acid SCHEMBL27689479 | 0.82 | FOLH1 (0.63) | FOLH1MRGPRX4CYP2D6CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524559-B | Ester derivant of polysubstituted 4-methylamino benzenecarboximidamide and its production and use | 西藏海思科药业集团股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-103201262-B | Autotaxin inhibitors and application thereof | AMIRA PHARMACEUTICALS, INC. (US) | 2016-06-01 | — | — | CN | disclosed |
| CN-102617580-A | Vasopressin V1a Antagonists | FERRING BV | 2012-08-01 | — | — | CN | disclosed |
| CN-102164899-A | 2, 3-substituted indazoles or 4,5,6, 7-tetrahydro-indazoles as FXR modulators against dyslipidemia and related diseases | HOFFMANN LA ROCHE | 2011-08-24 | — | — | CN | disclosed |
| US-7993494-B2 | Method for manufacturing triarylpyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20090183982-A1 | Method for Manufacturing Triarylpyrazine Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-07-23 | — | — | US | disclosed |