⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478140 | 0.83 | TSHR (0.65) | — | |
| SCHEMBL23729602 | 0.82 | TSHR (0.77) | — | |
| SCHEMBL310766 | 0.81 | — | — | |
| SCHEMBL3187649 | 0.81 | — | — | |
| SCHEMBL4814439 | 0.81 | — | — | |
| SCHEMBL13744495 | 0.81 | TSHR (0.52) | — | |
| SCHEMBL11395098 | 0.80 | SMN1; SMN2 (0.56) | — | |
| Methylene Chloride SCHEMBL27418043 | 0.80 | POLB (0.48) | — | |
| SCHEMBL458044 | 0.79 | — | — | |
| SCHEMBL41039 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472166-B2 | Inhibition of mycobacterial type VII secretion | STICHTING VUMC (NL) | 2025-11-18 | — | — | US | disclosed |
| EP-4021898-B1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | Stichting Amsterdam UMC (NL) | 2024-05-29 | — | — | EP | disclosed |
| US-20220280487-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | STICHTING VU (NL) | 2022-09-08 | — | — | US | disclosed |
| EP-4021898-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | Stichting VUmc (NL) | 2022-07-06 | — | — | EP | disclosed |
| EP-3908306-A1 | PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME | Yale University (US) | 2021-11-17 | — | — | EP | disclosed |
| CN-112679491-A | Thiazole amide derivative and preparation method and application thereof | 王俊涛 | 2021-04-20 | — | — | CN | disclosed |
| WO-2021040519-A1 | INHIBITION OF MYCOBACTERIAL TYPE VII SECRETION | STICHTING VUMC (NL) | 2021-03-04 | — | — | WO | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
| WO-2004048335-A2 | MANDELIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-06-10 | — | — | WO | disclosed |
| WO-1994008630-A1 | NOVEL COMPOSITIONS FOR MAGNETIC RESONANCE IMAGING | MALLINCKRODT MEDICAL, INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| EP-0592474-A1 | NOVEL COMPOSITIONS FOR MAGNETIC RESONANCE IMAGING | MALLINCKRODT MEDICAL, INC. (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5290537-A | Compositions for magnetic resonance imaging | MALLINCKRODT MEDICAL, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5208375-A | Compositions for magnetic resonance imaging | MALLINCKRODT MEDICAL, INC. (US) | 1993-05-04 | — | — | US | disclosed |
| WO-1993000931-A1 | NOVEL COMPOSITIONS FOR MAGNETIC RESONANCE IMAGING | MALLINCKRODT MEDICAL, INC. (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5138040-A | Composition for magnetic resonance imaging | MALLINCKRODT MEDICAL, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-4134766-A | COLOR PHOTOGRAPHY, PHENOL COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-01-16 | — | — | US | disclosed |
| US-3991140-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |
| US-3933945-A | O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |