Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478140 | 0.89 | TSHR (0.65) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL13498639 | 0.88 | TSHR (0.71) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL13501556 | 0.88 | CNR1 (0.67) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL14467685 | 0.88 | TSHR (0.66) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL23729609 | 0.87 | TSHR (0.59) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL13498640 | 0.86 | TSHR (0.75) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL15888692 | 0.86 | TSHR (0.69) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL18653344 | 0.86 | TSHR (0.63) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL15131897 | 0.86 | TSHR (0.69) | TSHRHPGDMEN1KMT2ACNR1 | |
| SCHEMBL7323180 | 0.86 | CNR1 (0.69) | TSHRHPGDCNR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |