Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LONP1 | P36776 | 15/20 | 1.00 |
| ▸ | PSMB5 | P28074 | 13/20 | 1.00 |
| ▸ | PSMB11 | A5LHX3 | 9/20 | 1.00 |
| ▸ | PSMA7 | O14818 | 9/20 | 1.00 |
| ▸ | PSMB1 | P20618 | 9/20 | 1.00 |
| ▸ | PSMA1 | P25786 | 9/20 | 1.00 |
| ▸ | PSMA2 | P25787 | 9/20 | 1.00 |
| ▸ | PSMA3 | P25788 | 9/20 | 1.00 |
| ▸ | PSMA4 | P25789 | 9/20 | 1.00 |
| ▸ | PSMB8 | P28062 | 9/20 | 1.00 |
| ▸ | PSMB9 | P28065 | 9/20 | 1.00 |
| ▸ | PSMA5 | P28066 | 9/20 | 1.00 |
| ▸ | PSMB4 | P28070 | 9/20 | 1.00 |
| ▸ | PSMB6 | P28072 | 9/20 | 1.00 |
| ▸ | PSMB10 | P40306 | 9/20 | 1.00 |
| ▸ | PSMB3 | P49720 | 9/20 | 1.00 |
| ▸ | PSMB2 | P49721 | 9/20 | 1.00 |
| ▸ | PSMA6 | P60900 | 9/20 | 1.00 |
| ▸ | PSMA8 | Q8TAA3 | 9/20 | 1.00 |
| ▸ | PSMB7 | Q99436 | 9/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21210367 | 1.00 | LONP1 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL15699269 | 1.00 | LONP1 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL3165922 | 0.88 | LONP1 (0.87) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL9608343 | 0.88 | LONP1 (0.85) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL25267933 | 0.85 | PSMB5 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL25267934 | 0.85 | PSMB5 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL25221893 | 0.85 | PSMB5 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL30406001 | 0.85 | PSMB5 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL15699267 | 0.82 | LONP1 (0.79) | LONP1PSMB5PSMB11PSMA7PSMB1 | |
| SCHEMBL10344951 | 0.82 | PSMB5 (1.00) | LONP1PSMB5PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220641-A2 | METHODS AND USES RELATED TO T CELL THERAPY AND PRODUCTION OF SAME | JUNO THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2020249527-A1 | COMBINATION THERAPY COMPRISING AN ANTI-CD25 ANTIBODY DRUG CONJUGATE AND A FURTHER AGENT | ADC THERAPEUTICS SA (CH) | 2020-12-17 | — | — | WO | disclosed |