Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1092509 | 0.81 | MAPT (0.56) | MAPTL3MBTL1GAANNMT | |
| SCHEMBL1092552 | 0.80 | MAPT (0.74) | MAPTL3MBTL1NNMTCXCR1CXCR2 | |
| SCHEMBL22773635 | 0.80 | MAPT (0.51) | MAPTL3MBTL1GAANNMTEPHX2 | |
| SCHEMBL29859242 | 0.80 | MAPT (0.50) | MAPTL3MBTL1GAANNMTEPHX2 | |
| SCHEMBL14480266 | 0.80 | MAPT (0.50) | MAPTL3MBTL1GAANNMTEPHX2 | |
| SCHEMBL2187452 | 0.80 | MAPT (0.50) | MAPTL3MBTL1GAANNMTKCNJ1 | |
| SCHEMBL22773699 | 0.78 | MAPT (0.50) | MAPTL3MBTL1GAACXCR1CXCR2 | |
| SCHEMBL19043133 | 0.78 | L3MBTL1 (0.73) | MAPTL3MBTL1GAAHRH3LMNA | |
| SCHEMBL2713919 | 0.76 | EPHX2 (0.60) | MAPTL3MBTL1EPHX2 | |
| SCHEMBL2185720 | 0.75 | MAPT (0.49) | MAPTL3MBTL1GAANNMTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020248065-A1 | UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2020-12-17 | — | — | WO | disclosed |