SCHEMBL2278732

SCHEMBL2278732

CC(C)N(C)C(=O)N(C1CCCCC1)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.49
HPGD P15428 1/20 0.48
GPR119 Q8TDV5 17/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5446083 0.82 EPHX1 (0.51) EPHX1HPGDGPR119
SCHEMBL5456521 0.82 EPHX1 (0.51) EPHX1HPGDGPR119
SCHEMBL2953243 0.81 EPHX1 (0.58) EPHX1HPGDGPR119
SCHEMBL2281275 0.81 EPHX1 (0.56) EPHX1HPGDGPR119
SCHEMBL2666135 0.80 GPR119 (0.55) EPHX1HPGDGPR119
SCHEMBL16376310 0.80 HPGD (0.51) EPHX1HPGDGPR119
SCHEMBL5449235 0.79 EPHX1 (0.53) EPHX1HPGDGPR119
SCHEMBL19717593 0.78 HPGD (0.56) EPHX1HPGDGPR119
SCHEMBL5195599 0.78 EPHX1 (0.49) EPHX1HPGDGPR119
SCHEMBL2278040 0.77 HPGD (0.53) EPHX1HPGDGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7989634-B2 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2011-08-02 US disclosed
EP-1685102-A4 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD (KR) 2008-08-20 EP disclosed
US-20070129346-A1 Melanocortin receptor agonists LG LIFE SCIENCES LTD. (KR) 2007-06-07 US disclosed
EP-1685102-A1 MELANOCORTIN RECEPTOR AGONISTS LG Life Sciences Ltd. (KR) 2006-08-02 EP disclosed
WO-2005047251-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2005-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129346-A1 Melanocortin receptor agonists MC1R, MC3R, MC5R EPHX1 2506/4885HPGD 1916/4885GPR119 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.