Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451586 | 1.00 | AGTR1 (0.46) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL2439774 | 0.88 | AGTR1 (0.48) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL12173191 | 0.85 | AGTR1 (0.53) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL28459373 | 0.84 | AGTR1 (0.46) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL14180252 | 0.84 | AGTR1 (0.46) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL28455057 | 0.83 | AGTR1 (0.58) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL3185 | 0.82 | AGTR1 (0.51) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL3011 | 0.82 | AGTR1 (0.51) | AGTR1LTB4R2ABCB11GP6ADAMTS4 | |
| SCHEMBL21619429 | 0.82 | AGTR1 (0.67) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL21619421 | 0.82 | AGTR1 (0.67) | AGTR1LTB4R2ABCB11GP6AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020248341-A1 | METHOD FOR PREPARING VALSARTAN | 宁波美诺华药业股份有限公司 | 2020-12-17 | — | — | WO | disclosed |
| CN-109761924-B | Improved post-treatment method of valsartan reaction mixed liquid | 安徽美诺华药物化学有限公司 | 2020-09-01 | — | — | CN | disclosed |