Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 13/20 | 0.41 |
| ▸ | UBA3 | Q8TBC4 | 13/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 8/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 8/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22787550 | 0.85 | NAE1 (0.42) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787468 | 0.85 | NAE1 (0.42) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787540 | 0.85 | NAE1 (0.42) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787514 | 0.80 | NAE1 (0.41) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL24286365 | 0.78 | NAE1 (0.41) | NAE1UBA3 | |
| SCHEMBL24286013 | 0.78 | SLC29A1 (0.46) | NAE1UBA3 | |
| SCHEMBL24286025 | 0.77 | NAE1 (0.44) | NAE1UBA3 | |
| SCHEMBL22787487 | 0.76 | AURKA (0.47) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL22787565 | 0.74 | NAE1 (0.39) | NAE1UBA3SAE1UBA2 | |
| SCHEMBL1797019 | 0.73 | NAE1 (0.36) | NAE1UBA3SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3985007-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020249109-A1 | TRIAZOLOPYRIMIDINE COMPOUND AND SALT, COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-17 | — | — | WO | disclosed |