Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359726 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL48866 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| Biphenyl SCHEMBL2997707 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL7738712 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL2999797 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL7739675 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL7741464 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL22284064 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL22284066 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 | |
| SCHEMBL231054 | 1.00 | ALDH1A1 (0.89) | ALDH1A1HSD17B10SLC18A3THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994311-B2 | Metal binding, electron donating dipyrrin functionality linked to electron withdrawing functionality, base to which chemosensor can be fixedly attached; for quantitative and qualitative sensing of +2 transition metals using ratiometric fluorescence capable of forming stable transition metal complex | STC. UNM (US) | 2011-08-09 | — | — | US | disclosed |